The period is the 1820's and the first wagon train leaves Independence heading west to Santa Fe. In order to maintain his power, the ruthless Official at Santa Fe must not let them arrive and he sends out his men to stop them. The wagon train then has to endure repeated attacks but is aided by a mysterious rider that shoots singing arrows and rides a painted stallion.

Tom Grant has found a rich gold vein and Bart Eaton is after it. Tom's sister Mary heads for the gold fields and Eaton and his men follow. Eaton teams up with Ace Daggett who plans to doublecross him and get the gold for himself. They frame Tom for murder and then try to get him to sign over his claim. The famous scout Tex Houston is on hand, escaping the attempts on his life, saving Mary from various perils, and trying to bring in the real killer and clear Tom.

Enemy spies try to steal a new fighter plane.

Hank Davis, foreman on a huge dam project, enlists the aid of his two flyer friends when a sinister figure known as The Black Ace leads his Mystery Squadron of masked pilots in an attempt to destroy the dam.

Texas Ranger tries to stop takeover of Indian lands.

Tom Wayne rescues Clancy, Renard and Schmidt in the Arabian desert and they join him in going after El Shaitan, a bad guy who is never seen as he tries to wipe out the Foreign Legion.

Strategic targets on Earth are being destroyed by an unknown weapon. Government security head Henderson suspects it's an "atomic ray" originating from the moon! He assigns Commando Cody, scientist and man of action with a secret flying suit, to investigate. Soon, Cody is battling Earth thugs in the pay of Krog the moon man and making trips in his experimental rocket to the moon itself, in a perilous and all but singlehanded effort to thwart the planned invasion of Earth.

Natty Bumppo, known as Hawk-Eye, is a frontiersman in the American wilderness. Together with his Indian friends Chingachgook and Uncas, he fights battles against nefarious white soldiers as well as the vicious Indian Magua and his cohorts.

Flash Gordon, Dale Arden and Dr. Zarkov return to the planet Mongo for an antidote to the Purple Death, which wreaking destruction on Earth. However, Ming the Merciless has other plans for them.

A master criminal called The Spider puts the famous detective's brother under a hypnotic spell and turns him against Dick.