When the ancient continent of Mu sank beneath the ocean, some of its inhabitant survived in caverns beneath the sea. Cowboy singer Gene Autry stumbles upon the civilization, now buried beneath his own Radio Ranch. The Muranians have developed technology and weaponry such as television and ray guns. Their rich supply of radium draws unscrupulous speculators from the surface. The peaceful civilization of the Muranians is corrupted by the greed from above, and it becomes Autry's task to prevent all-out war, ideally without disrupting his regular radio show.

Railroad detective Matt Clark roams the west, tracking down outlaws and bandits who are preying on the railroad.

A frontier newspaper editor Kirby battles outlaw Tiger Morris who is causing indian uprisings to drive away settlers so that he will can claim a gold deposit as his own. With the help of General Custer, right wins out. Presented in serial form in 12 episodes.

Buck Sherman and Jake Jackson, a couple of evil carpetbaggers, illegally enter a Navajo reservation to prospect for gold and end up killing Aranho, the Navajos chief. Black Arrow, presumed Aranho's son, refuses to kill the Indian agent, Tom Whitney, in revenge, as demanded by Navajo law. Then, he is driven off the reservation for his reluctance to kill Whitney and decides to join forces with Pancho, Mary Brent and the agent to go in search of the men who killed the chief.

A prospector is murdered by The Cactus Kid and his gang, who hope to find the murdered man's goldmine. The miner's dog, Rin-Tin-Tin, recognizes the killers, who thereafter seek to use the dog to locate the lost mine. With the help of a government agent and a young girl, Rinty saves the mine and brings the bad guys to justice.

A 12 episode serial starring Rex, the King of the Wild Horses and Rin-Tin-Tin, Jr. Rex is brought from the island of Sujan, where he is worshiped as a God-Horse, to the U.S. to be trained as a polo pony. He escapes, meets Rinty and with the help of Frank Bradley is returned to Sujan. The natives have been persuaded to turn against their God-Horse, however he is rescued just in time before he is burned as a sacrifice.

The adventures of a small town doctor working in the Arizona territory during the early 1900s.

Cowboys and a businessman compete to find lost treasure.