This show featured four rotating stars, Charles Boyer, David Niven, Ida Lupino, and Dick Powell in individual episodes consisting of everything from comedy to drama.

The period is the 1820's and the first wagon train leaves Independence heading west to Santa Fe. In order to maintain his power, the ruthless Official at Santa Fe must not let them arrive and he sends out his men to stop them. The wagon train then has to endure repeated attacks but is aided by a mysterious rider that shoots singing arrows and rides a painted stallion.

Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.

New York City policewoman Casey Jones' assignment to fight crime often entails her going undercover in some of the seediest and most dangerous parts of the city.

Deadwood Dick, a masked and mysterious hero, is in reality Dick Stanley, editor of the Dakota Pioneer Press and a leading member of Statehood For Dakota. He is on the trail of a masked villain known as the Skull, who leads a violent, renegade band infamous for its violence against the Deadwood residents' wishes for a statehood status.

Enemy spies try to steal a new fighter plane.

Texas Ranger tries to stop takeover of Indian lands.

A young girl journeys to Africa to find her father, an explorer who vanished in the jungle.