Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.
Former combat cameraman Mike Kovac is now a freelance photographer in New York City, specializing in difficult and dangerous assignments where he can get the kinds of pictures that other photographers can't, or won't take. He sometimes gets help, often reluctantly, from his contact in the police department, Lt. Donovan, and advice from his immigrant father Anton.
Natty Bumppo, known as Hawk-Eye, is a frontiersman in the American wilderness. Together with his Indian friends Chingachgook and Uncas, he fights battles against nefarious white soldiers as well as the vicious Indian Magua and his cohorts.
Highlights the personal and professional lives of a group of doctors and surgeons headed by Dr. Konrad Styner. One of the first medical shows on TV that paid strict attention to detail, and heralded at the time for its sometimes unflinching look at the operations and medical procedures performed by doctors.
Secret Service Major Steel (Joseph W. Girard), is one of the few men in America aware of the fact that Captain Albright (Dave O'Brien) is also Captain Midnight, daring masked aviator dedicated to fighting gangsters and enemies of America. When murderous bombing attacks are made on West Coast munitions plants, Steel sends for Albright and asks him to track down the mysterious Ivan Shark (James Craven), the foreign agent mastermind behind the attacks. Shark has learned about an ingenious range finder, invented by John Edwards (Bryant Washburn, and makes plans to obtain a model of the invention. Edwards instructs his daughter, Joyce (Dorothy Short), to bring the model to Albright for safekeeping in his mountain laboratory. Shark takes Edwards prisoner by Albright assures Joyce that her father will be saved and an end put to Shark's reign of terror. Dressing as Captain Midnight and enlisting the aid of his friends, Chuck (Sam Edwards) and Ichabod Mudd (Guy Wilkerson), Captain Midnight delivers on his promises fourteen chapters later.
Captain Dan Tempest was an ex-pirate who received a pardon from the King and turned privateer after his stronghold of New Providence was taken over by Crown soldiers. Tempest and Lt. Beamish, the Crown-appointed deputy governor, were uneasy allies, fighting the Spanish privateers who were ravaging the Caribbean.