Secret Service Major Steel (Joseph W. Girard), is one of the few men in America aware of the fact that Captain Albright (Dave O'Brien) is also Captain Midnight, daring masked aviator dedicated to fighting gangsters and enemies of America. When murderous bombing attacks are made on West Coast munitions plants, Steel sends for Albright and asks him to track down the mysterious Ivan Shark (James Craven), the foreign agent mastermind behind the attacks. Shark has learned about an ingenious range finder, invented by John Edwards (Bryant Washburn, and makes plans to obtain a model of the invention. Edwards instructs his daughter, Joyce (Dorothy Short), to bring the model to Albright for safekeeping in his mountain laboratory. Shark takes Edwards prisoner by Albright assures Joyce that her father will be saved and an end put to Shark's reign of terror. Dressing as Captain Midnight and enlisting the aid of his friends, Chuck (Sam Edwards) and Ichabod Mudd (Guy Wilkerson), Captain Midnight delivers on his promises fourteen chapters later.

A newspaper publisher and his Korean servant fight crime as vigilantes who pose as a notorious masked gangster and his aide.

Former combat cameraman Mike Kovac is now a freelance photographer in New York City, specializing in difficult and dangerous assignments where he can get the kinds of pictures that other photographers can't, or won't take. He sometimes gets help, often reluctantly, from his contact in the police department, Lt. Donovan, and advice from his immigrant father Anton.

Texas Ranger tries to stop takeover of Indian lands.

Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.

A crime fighter known as The Spider battles a villain called The Octopus, who is out to sabotage America and install his own government.

New York City policewoman Casey Jones' assignment to fight crime often entails her going undercover in some of the seediest and most dangerous parts of the city.

This show featured four rotating stars, Charles Boyer, David Niven, Ida Lupino, and Dick Powell in individual episodes consisting of everything from comedy to drama.