The period is the 1820's and the first wagon train leaves Independence heading west to Santa Fe. In order to maintain his power, the ruthless Official at Santa Fe must not let them arrive and he sends out his men to stop them. The wagon train then has to endure repeated attacks but is aided by a mysterious rider that shoots singing arrows and rides a painted stallion.

When his father is killed in a train wreck, Larry Baker vows to unmask a mysterious criminal called "The Wrecker," who has targeted the L&M Railroad for deadly" accidents."

Tom Grant has found a rich gold vein and Bart Eaton is after it. Tom's sister Mary heads for the gold fields and Eaton and his men follow. Eaton teams up with Ace Daggett who plans to doublecross him and get the gold for himself. They frame Tom for murder and then try to get him to sign over his claim. The famous scout Tex Houston is on hand, escaping the attempts on his life, saving Mary from various perils, and trying to bring in the real killer and clear Tom.

A scientist discovers a formula for making synthetic gold.

Beyond Hell's Gate Pass is territory controlled by a man who calls himself King Carter; he uses a variety of schemes to prevent the railroad from being built, for fear it will finish his control of (what he considers) his land.

Tom Wayne rescues Clancy, Renard and Schmidt in the Arabian desert and they join him in going after El Shaitan, a bad guy who is never seen as he tries to wipe out the Foreign Legion.

Young Pauline is left a lot of money when her wealthy uncle dies. However, her uncle's secretary has been named as her guardian until she marries, at which time she will officially take possession of her inheritance. Meanwhile, her "guardian" and his confederates constantly come up with schemes to get rid of Pauline so that he can get his hands on the money himself.

Corporal Larry Grant and Sergeant "Mac" McGowan, of the United States Marine Corps, are rival for the love of Frances Schiller, but team up to hunt down "The Tiger Shark," a mad, scientific wizard who is holding Sergeant William Schiller, Frances' brother, a prisoner on a wild, jungle island in the Pacific.

American adventurer Richard Grant is falsely accused of murdering an Indian noble and escapes to Africa in search of diamond field and the real culprit.

The masked hero leads a fighting force to fight a villian who plots the conquest of The Republic of Mexico.