The Cisco Kid and his English-mangling sidekick Pancho travel the old west in the grand tradition of the Lone Ranger, righting wrongs and fighting injustice wherever they find it.

Railroad detective Matt Clark roams the west, tracking down outlaws and bandits who are preying on the railroad.

A frontier newspaper editor Kirby battles outlaw Tiger Morris who is causing indian uprisings to drive away settlers so that he will can claim a gold deposit as his own. With the help of General Custer, right wins out. Presented in serial form in 12 episodes.

Nat Cutler, known as Hawkeye, is a fur trader. With his faithful Indian companion Chingachgook, the last of the Mohican tribe, he fights to protect settlers against the raiding Huron Indians.

A masked hero called "The Eagle" leads California ranchers in a struggle against Russian Cossacks who are plotting to take over California and turn it into a Russian colony.

A prospector is murdered by The Cactus Kid and his gang, who hope to find the murdered man's goldmine. The miner's dog, Rin-Tin-Tin, recognizes the killers, who thereafter seek to use the dog to locate the lost mine. With the help of a government agent and a young girl, Rinty saves the mine and brings the bad guys to justice.

When the ancient continent of Mu sank beneath the ocean, some of its inhabitant survived in caverns beneath the sea. Cowboy singer Gene Autry stumbles upon the civilization, now buried beneath his own Radio Ranch. The Muranians have developed technology and weaponry such as television and ray guns. Their rich supply of radium draws unscrupulous speculators from the surface. The peaceful civilization of the Muranians is corrupted by the greed from above, and it becomes Autry's task to prevent all-out war, ideally without disrupting his regular radio show.