Rex, a wild stallion, and Rinty, a police dog, are pals. Their master , John Sheldon, is framed for murder, and Alice Ingram plans to race Rex for money to pay for John's legal defense. Meantime, Frank Nolan, who has falsely accused John, sets out to steal Rex for himself.

In this Western, comprised of 12 chapters from a serial, Kit leads a group carrying a large gold shipment across the wild West. When the Mystery Riders attack and steal the gold, Kit is the only survivor. He later joins forces with the cavalry to retrieve it.

Nat Cutler, known as Hawkeye, is a fur trader. With his faithful Indian companion Chingachgook, the last of the Mohican tribe, he fights to protect settlers against the raiding Huron Indians.

Railroad detective Matt Clark roams the west, tracking down outlaws and bandits who are preying on the railroad.

A western adventure serial in 12 episodes. Buffalo Bill battles gambler Jim Rodney who is trying to scare off the townspeople so he can gain possession of a gold strike discovered in the area. A nearby Indian tribe is provoked to attack the town and the cavalry is called in.