When the ancient continent of Mu sank beneath the ocean, some of its inhabitant survived in caverns beneath the sea. Cowboy singer Gene Autry stumbles upon the civilization, now buried beneath his own Radio Ranch. The Muranians have developed technology and weaponry such as television and ray guns. Their rich supply of radium draws unscrupulous speculators from the surface. The peaceful civilization of the Muranians is corrupted by the greed from above, and it becomes Autry's task to prevent all-out war, ideally without disrupting his regular radio show.

The Cisco Kid and his English-mangling sidekick Pancho travel the old west in the grand tradition of the Lone Ranger, righting wrongs and fighting injustice wherever they find it.

In 1865, Captain Mark Smith of the Confederate Army leads a band of deserters to conquer Texas and rule it as a dictator. In one of his first actions, he captures and assumes the identity of Texas' new Finance Commissioner, Colonel Marcus Jeffries, after having the real man murdered. When a contingent of Texas Rangers enters the territory, Snead, one of Smith's men, leads them into an ambush by Smith's "troopers". The Rangers are apparently wiped out, although one injured survivor is left. The survivor, nursed back to health by Tonto, swears to avenge the massacre and defeat "Colonel Jeffries" and his men.

The Wild West adventures of Ben Cartwright and his sons as they run and defend their Nevada ranch while helping the surrounding community.

A stage and a wagon heading west get separated from the rest of the wagon train thanks to Dusty. Now they must make their way to California.

A mysterious master criminal known as The Voice plots with his gang to sabotage the Milesburg Oil Company, but the rightful heir has a secret army of her own to protect her rights.