When the ancient continent of Mu sank beneath the ocean, some of its inhabitant survived in caverns beneath the sea. Cowboy singer Gene Autry stumbles upon the civilization, now buried beneath his own Radio Ranch. The Muranians have developed technology and weaponry such as television and ray guns. Their rich supply of radium draws unscrupulous speculators from the surface. The peaceful civilization of the Muranians is corrupted by the greed from above, and it becomes Autry's task to prevent all-out war, ideally without disrupting his regular radio show.

A stage and a wagon heading west get separated from the rest of the wagon train thanks to Dusty. Now they must make their way to California.

The Wild West adventures of Ben Cartwright and his sons as they run and defend their Nevada ranch while helping the surrounding community.

A mysterious master criminal known as The Voice plots with his gang to sabotage the Milesburg Oil Company, but the rightful heir has a secret army of her own to protect her rights.

Nat Cutler, known as Hawkeye, is a fur trader. With his faithful Indian companion Chingachgook, the last of the Mohican tribe, he fights to protect settlers against the raiding Huron Indians.

Railroad detective Matt Clark roams the west, tracking down outlaws and bandits who are preying on the railroad.