A crime fighter known as The Spider battles a villain called The Octopus, who is out to sabotage America and install his own government.

Secret Service Major Steel (Joseph W. Girard), is one of the few men in America aware of the fact that Captain Albright (Dave O'Brien) is also Captain Midnight, daring masked aviator dedicated to fighting gangsters and enemies of America. When murderous bombing attacks are made on West Coast munitions plants, Steel sends for Albright and asks him to track down the mysterious Ivan Shark (James Craven), the foreign agent mastermind behind the attacks. Shark has learned about an ingenious range finder, invented by John Edwards (Bryant Washburn, and makes plans to obtain a model of the invention. Edwards instructs his daughter, Joyce (Dorothy Short), to bring the model to Albright for safekeeping in his mountain laboratory. Shark takes Edwards prisoner by Albright assures Joyce that her father will be saved and an end put to Shark's reign of terror. Dressing as Captain Midnight and enlisting the aid of his friends, Chuck (Sam Edwards) and Ichabod Mudd (Guy Wilkerson), Captain Midnight delivers on his promises fourteen chapters later.

This show featured four rotating stars, Charles Boyer, David Niven, Ida Lupino, and Dick Powell in individual episodes consisting of everything from comedy to drama.

The adventures of master detective Sherlock Holmes as he and his assistant, Dr. Watson--and, somewhat reluctantly, the bumbling Inspector Lestrade--battle criminals in London.

The period is the 1820's and the first wagon train leaves Independence heading west to Santa Fe. In order to maintain his power, the ruthless Official at Santa Fe must not let them arrive and he sends out his men to stop them. The wagon train then has to endure repeated attacks but is aided by a mysterious rider that shoots singing arrows and rides a painted stallion.

Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.

Tom Wayne rescues Clancy, Renard and Schmidt in the Arabian desert and they join him in going after El Shaitan, a bad guy who is never seen as he tries to wipe out the Foreign Legion.

A young girl journeys to Africa to find her father, an explorer who vanished in the jungle.